UNDATED (AP) — Major League Baseball launched the expanded replay era Monday, and saw instant results — a pair of missed calls by umpires got fixed fast, without any arguments.

Opening day showed off the game's newest nod to modern technology in a sport that long relied on the eyes of its umps.

In Pittsburgh, Cubs manager Rick Renteria (rehn-ter-EE'-uh) was the first skipper to challenge a play under the new expanded replay system. After review, which took about two minutes, the decision by the umpires was upheld.

The first overturned call came in Milwaukee. Atlanta Braves manager Fredi Gonzalez challenged the sixth-inning play at Miller Park in the season opener won by Milwaukee, 2-0. Brewers star Ryan Braun was originally called safe at first base by umpire Greg Gibson on a leadoff infield single fielded by third baseman Chris Johnson. The call was reversed to out after a review that lasted 58 seconds, and Braun ran back to the dugout.

From now on, most every call can be challenged by a manager. When that happens, the final decision will come from a replay booth in New York, rather than the field. And instead of out or safe, fair or foul, disputes will be settled with two words new to baseball's lingo: confirmed or overturned.

UNDATED (AP) — On the first nearly full schedule of major league games, Yadier Molina's (YAH'-dee-eer moh-LEE'-nahz) homer broke a seventh-inning scoreless tie in the St. Louis Cardinals' 1-0 victory over the Cincinnati Reds. The Reds were blanked on opening day for the first time since 1953.

That ended the second-longest streak of scoring at least one run in season openers in major league history. The Phillies went 62 years without being blanked in an opener from 1911-72.

Adam Wainwright and four Cards relievers combined on the three-hit shutout.

Here's are other NL results:

— Neil Walker homered leading off the bottom of the tenth to give Pittsburgh a 1-0 win over the Cubs. It was the first opening-day walkoff homer for the Pirates since Bob Bailey's off San Francisco's Juan Marichal in a 1-0 victory in 1965.

— Yovani Gallardo (yoh-VAH'-nee gy-AR'-doh) scattered four hits in six innings to lead the Brewers to a 2-0 win over Atlanta. Ryan Braun returned to the Milwaukee line-up for the first time since serving a 65-game drug suspension last season. He got a standing ovation.

— Anthony Rendon (rehn-DOHN') hit a three-run homer to cap a fourth-run tenth to give Washington a 9-7 win over the Mets. The Nationals' Stephen Strasburg struck out 10 while allowing five runs on four hits in six innings.

— Miami routed Colorado 10-1. Marlins ace Jose Fernandez struck out nine and allowed one run in six innings. Marlins newcomer Casey McGehee (mih-GEE') drove in four runs with two doubles.

— San Francisco beat Arizona 9-8. Buster Posey hit a two-run homer off new Arizona closer Addison Reed in the ninth inning and the Giants rallied from four runs down.

— In an interleague game, Jimmy Rollins hit a grand slam to power Philadelphia to a 14-10 win at Texas. Starter Cliff Lee got the win for the Phillies despite giving up eight runs on 11 hits in five innings.

Over in the AL:

— David Price took a shutout into the eighth inning and Matt Joyce drove in three runs to help the Tampa Bay Rays begin the season with a 9-2 victory over the Toronto Blue Jays.

— Alex Gonzalez made his Tigers debut memorable with the game-winning single in the bottom of the ninth of a 4-3 win over Kansas City. He also tied the game in the seventh with an RBI triple. Gonzalez was acquired by Detroit last week after starting shortstop Jose Iglesias went down with an injury. Gonzalez's hitting heroics made up for a costly error he made in a three-run Kansas City fourth.

— Alejandro De Aza hit two homers, and Jose Abreu had two hits in his major league debut to back Chris Sale and lead the Chicago White Sox to a 5-3 season-opening victory over the Minnesota Twins. Paul Konerko, the White Sox' 38-year-old first baseman, didn't get into the game but got a loud ovation before what was likely his final opener.

— Justin Smoak broke open a close game with a three-run home run in the top of the ninth to help Seattle beat the L.A. Angels 10-3.

— Cleveland broke a scoreless deadlock with a couple of runs in the top of the ninth to beat Oakland 2-0. Justin Masterson and three relievers combined on the five-hit shutout.

— Nelson Cruz celebrated his Orioles debut with a tie-breaking home run in a season-opening 2-1 win over World Series champ Boston.